产品货号：
Z19575
中文名称：
JMJD1C抗体
英文名称：
Anti-JMJD1C Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-JMJD1C Antibody |
| 指标别名 | TRIP8,JHDM2C,KIAA1380,TRIP8,Probable JmjC domain-containing histone demethylation protein 2C,Jumonji domain-containing protein 1C,TR-interacting protein 8 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | JMJD1C |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | JMJD1C antibody was raised against a 20 amino acid synthetic peptide from near the amino terminus of human JMJD1C.The immunogen is located within amino acids 380 - 430 of JMJD1C. |
| 计算分子量 | 285kDa |
| 成分 | JMJD1C Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | JMJD1C Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico,and later suggested to be a candidate gene for autism.Like the related proteins JMJD1A and JMJD1B,JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation.JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet,diffuse-type gastric cancer,and other tissues and tumors.The JMJD1C gene promoter contain bHLH-,AP-1-,and POU5F1-binding sites,and as preferential expression of POU5F1 has been reported in ES cells,pancreatic islet,and diffuse-type gastric cancer,it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer.At least three isoforms of JMJD1C are known to exist. |
| Uniprot ID | Q15652 |
| 基因名全称 | Jumonji domain containing 1C |
| 蛋白名全称 | Jumonji domain containing 1C |
| 推荐稀释比 | JMJD1C antibody can be used for detection of JMJD1C by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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